Sunderland boss Sam Allardyce will be without Lee Cattermole for their Premier League clash with Southampton at the Stadium of Light on Saturday.
Cattermole limped out of last week's 6-2 defeat at Everton with a recurrence of a long-standing groin problem and has been ruled out until after the international break.
But John O'Shea (hamstring), Younes Kaboul (groin), Ola Toivonen (groin) and Fabio Borini (ankle) are all available for selection again after missing last week's defeat due to injury.
Victor Wanyama will miss out for Southampton after picking up a one-match ban.
Wanyama was sent off for a second bookable offence towards the end of last week's victory over Bournemouth, and Harrison Reed could step up to the team for the clash against Sam Allardyce's men.
Jay Rodriguez and Shane Long are once again unable to feature despite both forwards inching towards full fitness after knee and foot injuries respectively.
Sunderland squad: Pantilimon, Mannone, Jones, Van Aanholt, Yedlin, Matthews, O'Shea, Kaboul, Coates, Brown, M'Vila, Larsson, Gomez, Johnson, Toivonen, Lens, Borini, Defoe, Fletcher, Watmore.
Southampton squad: Stekelenburg, K Davis, Gazzaniga, Soares, Martina, Caulker, Yoshida, Van Dijk, Fonte, Bertrand, Targett, Clasie, S Davis, Reed, Romeu, Ward-Prowse, Mane, Juanmi, Ramirez, Tadic, Pelle.
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